Because I had a friend ask me for a local charity or ministry that would take knitted baby hats, I did some asking and found out that a wonderful local organization called
Tricounty Family Ministries will gladly take knitted (or crocheted!) items. They also have a current need for clothing, as they have given out all their clothing to the less fortunate in the Tricounty area.
You can also volunteer there in many different capacities as well.
I know there are a multitude of charities that take knitted items, both in this country and around the world, but if you ever want to help folks in your own backyard (and you live in the Charleston, SC area), this is a good option. And think of all the postage you'll save :)